You can actively contribute to the development of the IARC TP53 Database by submitting data directly to us at
At the present time we only accept data that have been accepted for publication in peer-reviewed journals.
Mutation must be described at the nucleotide level.
To submit data, you can either send your own electronic file or use the IARC submission form:
download form and instructions
(2 Excel files and 1 Word file in a compressed zip format).
The reference genomic sequence used for TP53 from R17 is NC_000017.10 (hg19).
To convert position of mutations from g. to c. or between different genome builds, we recommend to use Mutalizer.
Reporting in scientific journals