How to contribute data to the database

General guidelines for reporting and submiting somatic mutation data have been published in:

Somatic mutation databases as tools for molecular epidemiology and molecular pathology of cancer: proposed guidelines for improving data collection, distribution, and integration.
Olivier M, Petitjean A, Teague J, Forbes S, Dunnick JK, den Dunnen JT, Langerød A, Wilkinson JM, Vihinen M, Cotton RG, Hainaut P; IARC; EC FP6. Hum Mutat.2009 Mar;30(3):275-82. PubMed

Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer.
Li MM, Datto M, Duncavage EJ, Kulkarni S, Lindeman NI, Roy S, Tsimberidou AM, Vnencak-Jones CL, Wolff DJ, Younes A, Nikiforova MN. J Mol Diagn. 2017 Jan;19(1):4-23. PubMed

Further guidelines are provided below.

Direct submission

You can actively contribute to the development of the IARC TP53 Database by submitting data directly to us at . At the present time we only accept data that have been accepted for publication in peer-reviewed journals. Mutation must be described at the nucleotide level.

To submit data, you may use the IARC submission forms: download forms.

You may submit data using hg19 or hg38 genome build. We recommend using NM_000546 reference transcript.

To convert position of mutations from g. to c. or between different genome builds, we recommend to use Mutalizer.

Reporting in scientific journals
Reply to data requests